BDBM208501 US9266870, 17::US9266870, 22

SMILES Cc1ccc(c(c1)C(=O)N1CCOC1Cn1ccc(n1)-c1ccc(F)cc1)-n1nccn1

InChI Key InChIKey=GUQHPENKNGCHKL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 208501   

TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208501(US9266870, 22 | US9266870, 17)
Affinity DataIC50: 5.10nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208501(US9266870, 22 | US9266870, 17)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208501(US9266870, 22 | US9266870, 17)
Affinity DataIC50: 46.7nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208501(US9266870, 22 | US9266870, 17)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent