BDBM208498 US9266870, 14

SMILES Cc1ccc(c(c1)C(=O)N1CCOC1Cn1ccc(n1)-c1ccc(F)cn1)-c1ncccn1

InChI Key InChIKey=MTRMGWUUXSFEBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 208498   

TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208498(US9266870, 14)
Affinity DataIC50: 9.70nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208498(US9266870, 14)
Affinity DataIC50: 9.5nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent