BDBM208380 US9266835, 42

SMILES CC(C)(C)OC(=O)N1CC(CNc2cc(=O)[nH]c3ccc(cc23)C(c2nccs2)c2ccc(Cl)cc2)C1

InChI Key InChIKey=MNIPANZRLRIDDG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 208380   

TargetCannabinoid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM208380(US9266835, 42)
Affinity DataEC50:  2.33E+3nMAssay Description:The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM208380(US9266835, 42)
Affinity DataEC50:  2.33E+3nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed