BDBM20811 2-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-3,5-dimethylpyridine-4-carbonitrile::2-amino-6-halopurine analogue, 33

SMILES Cc1cnc(Cn2cnc3c(Cl)nc(N)nc23)c(C)c1C#N

InChI Key InChIKey=RENRYXWKQYUUPE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20811   

TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

LigandPNGBDBM20811(2-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-3,5-dim...)
Affinity DataEC50:  990nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2008
Entry Details Article
PubMed