BDBM20791 2-amino-6-halopurine analogue, 18c::6-chloro-9-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-9H-purin-2-amine

SMILES COc1cc(Cn2cnc3c(Cl)nc(N)nc23)c(I)c(OC)c1OC

InChI Key InChIKey=OXGASDFRBCWQOD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20791   

TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

LigandPNGBDBM20791(6-chloro-9-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]...)
Affinity DataEC50:  340nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2008
Entry Details Article
PubMed