BDBM20788 2-amino-6-halopurine analogue, 17::6-chloro-9-[(3,4,5-trimethoxyphenyl)methyl]-9H-purin-2-amine

SMILES COc1cc(Cn2cnc3c(Cl)nc(N)nc23)cc(OC)c1OC

InChI Key InChIKey=BLVDRYKMRPWIBL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20788   

TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

LigandPNGBDBM20788(6-chloro-9-[(3,4,5-trimethoxyphenyl)methyl]-9H-pur...)
Affinity DataEC50:  2.00E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2008
Entry Details Article
PubMed