BDBM20786 3-[6-amino-8-({7-chloropyrido[3,4-d][1,3]thiazol-2-yl}sulfanyl)-9H-purin-9-yl]propyl acetate::Pyridothiazole analogue, 30

SMILES CC(=O)OCCCn1c(Sc2nc3cncc(Cl)c3s2)nc2c(N)ncnc12

InChI Key InChIKey=FONWXTBTYUBXDF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20786   

TargetHeat shock protein HSP 90-beta(Human)
Conforma Therapeutics

LigandPNGBDBM20786(3-[6-amino-8-({7-chloropyrido[3,4-d][1,3]thiazol-2...)
Affinity DataEC50:  170nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2008
Entry Details Article
PubMed