BDBM207637 BDBM207672::US9265734, R08::US9796664, Compound R08

SMILES Nc1ccccc1NC(=O)CCCCCNS(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=SNKHVLQDMDSYMB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 207637   

TargetHistone deacetylase 1(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM207637(US9265734, R08 | BDBM207672 | US9796664, Compound ...)
Affinity DataIC50: 2.40E+4nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM207637(US9265734, R08 | BDBM207672 | US9796664, Compound ...)
Affinity DataIC50: 3.60E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM207637(US9265734, R08 | BDBM207672 | US9796664, Compound ...)
Affinity DataIC50: 4.60E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM207637(US9265734, R08 | BDBM207672 | US9796664, Compound ...)
Affinity DataIC50: 4.00E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM207637(US9265734, R08 | BDBM207672 | US9796664, Compound ...)
Affinity DataIC50: 2.40E+4nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM207637(US9265734, R08 | BDBM207672 | US9796664, Compound ...)
Affinity DataIC50: 3.60E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent