BDBM207628 US9265734, RGFA8::US9796664, Compound RGFA8
SMILES Cc1ccc(NC(=O)CCCCCC(=O)Nc2ccccc2N)cc1
InChI Key InChIKey=WTKBRPXPNAKVEQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 207628
Affinity DataIC50: 2.00E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human HDAC3 expressed in baculovirus infected HEK293T cells using acetylLys(Ac)-AMC as substrate preincubated for 3 hrs fol...More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Inhibition of recombinant human HDAC1 expressed in baculovirus infected HEK293T cells using acetylLys(Ac)-AMC as substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant human HDAC3 expressed in baculovirus infected HEK293T cells using acetylLys(Ac)-AMC as substrate preincubated upto 3 hrs fo...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant human HDAC1 expressed in baculovirus infected HEK293T cells using acetylLys(Ac)-AMC as substrate preincubated upto 3 hrs fo...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
Affinity DataIC50: 3.73E+3nMAssay Description:HDAC inhibition assays can be performed, e.g., in a cell, in a cell extract, or in a cell-free mixture. Exemplary HDAC inhibition assays are describe...More data for this Ligand-Target Pair
Affinity DataIC50: 3.05E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 3.73E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 6.62E+4nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataIC50: 3.73E+3nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity to recombinant human HDAC3 expressed in baculovirus infected HEK293T cells using acetylLys(Ac)-AMC as substrate assessed as inhibiti...More data for this Ligand-Target Pair
Affinity DataKi: 148nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in sf9 cells using acetyl-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 148nMAssay Description:Binding affinity to recombinant human HDAC1 expressed in baculovirus infected HEK293T cells using acetylLys(Ac)-AMC as substrate assessed as inhibiti...More data for this Ligand-Target Pair