BDBM207561 US10501467, Example 6::US9260440, 6::US9617273, Example 6

SMILES CC(C)C1Cc2[nH]c3cccc4c3c2c(C1)n[nH]c4=O

InChI Key InChIKey=WELSPTLZWKCYMB-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 207561   

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 6nMpH: 8.0Assay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/9/2017
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 1.10nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/9/2017
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 80nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/9/2017
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 1.10E+3nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 8.00E+4nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 1.10E+3nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Beigene

US Patent
LigandPNGBDBM207561(US9260440, 6 | US9617273, Example 6 | US10501467, ...)
Affinity DataIC50: 8.00E+4nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent