BDBM20748 8-[(2-iodo-5-methoxyphenyl)sulfanyl]-9-[3-(pentan-3-ylamino)propyl]-9H-purin-6-amine::Amine, 37

SMILES CCC(CC)NCCCn1c(Sc2cc(OC)ccc2I)nc2c(N)ncnc12

InChI Key InChIKey=ZISPNJILQDJGRR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20748   

TargetHeat shock protein HSP 90-beta(Human)
Conforma Therapeutics

LigandPNGBDBM20748(8-[(2-iodo-5-methoxyphenyl)sulfanyl]-9-[3-(pentan-...)
Affinity DataEC50:  210nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed