BDBM20721 (1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino}phenyl)phenyl]carbonyl}cyclopentane-1-carboxylic acid::Urea-based Analogue, 4e

SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1

InChI Key InChIKey=NMTNXSFVPYVROS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20721   

TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20721((1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20721((1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino...)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed