BDBM206495 US9260425, 245::US9260425, 340

SMILES N[C@H]1CCC[C@H](C1)Nc1cccc(n1)-c1n[nH]c2cnc(cc12)-c1cccnc1

InChI Key InChIKey=FWMVELRLCYRLLJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206495   

TargetSerine/threonine-protein kinase pim-1(Human)
Genetech

US Patent
LigandPNGBDBM206495(US9260425, 340 | US9260425, 245)
Affinity DataKi:  0.00790nMpH: 7.2Assay Description:PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Genetech

US Patent
LigandPNGBDBM206495(US9260425, 340 | US9260425, 245)
Affinity DataKi:  0.0440nMpH: 7.2Assay Description:PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
Go to US Patent