BDBM20637 2-(3-fluoro-4-hydroxyphenyl)-1-benzothiophene-4,6-diol::benzthiophene compound, 12

SMILES Oc1cc(O)c2cc(sc2c1)-c1ccc(O)c(F)c1

InChI Key InChIKey=FHRLXXNPJFFTRA-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20637   

TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20637(2-(3-fluoro-4-hydroxyphenyl)-1-benzothiophene-4,6-...)
Affinity DataIC50: 1.00E+4nM EC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20637(2-(3-fluoro-4-hydroxyphenyl)-1-benzothiophene-4,6-...)
Affinity DataIC50: 7.47E+3nM EC50: >1.00E+3nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed