BDBM20621 1-{4-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl}-2-(3-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinolin-6-ol::Piperazine Derivative, 48

SMILES Oc1cccc(c1)N1CCc2cc(O)ccc2C1c1ccc(cc1)N1CCN(CC2CC2)CC1

InChI Key InChIKey=RKEFNNDFHCTSIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20621   

TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20621(1-{4-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl}-...)
Affinity DataIC50: 122nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20621(1-{4-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl}-...)
Affinity DataIC50: 1.37E+3nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed