BDBM206130 US9255110, 43

SMILES COc1cc2ncccc2cc1NC(=O)c1csc2cnc(NC3CC3)nc12

InChI Key InChIKey=JFKRMJRQGVELFG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 206130   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM206130(US9255110, 43)
Affinity DataIC50: 74nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM206130(US9255110, 43)
Affinity DataIC50: 575nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM206130(US9255110, 43)
Affinity DataIC50: 810nMpH: 7.2 T: 2°CAssay Description:SYK activity is measured by phosphorylation of a peptide substrate (Biotin-EPEGDYEEVLE) with [gamma-33P] ATP. The enzyme reaction was conducted at 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent