BDBM206052 (4aR)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-N- (2,6-dioxopiperidin-3-yl)-1,2,3,4,4a,5- hexahydropyrazino[1,2-d]pyrido[2,3- b][1,4]oxazine-8-carboxamide::US20260007681, Compound A51

SMILES COc1cc(N2CCC(CN3CCN4c5ccc(C(=O)NC6CCC(=O)NC6=O)nc5OC[C@H]4C3)CC2)ccc1[C@@H]1c2[nH]c3ccccc3c2C[C@@H](C)N1CC(F)F

InChI Key InChIKey=VPOZGRAOIJNXPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206052   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206052BDBM206052((4aR)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-m...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206052BDBM206052((4aR)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-m...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent