BDBM20605 2-[3-(dimethylamino)phenyl]-1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol::tetrahydroisoquinoline derivative, 20j

SMILES CN(C)c1cccc(c1)N1CCc2cc(O)ccc2C1(C)c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=RPGDQMYAMWXMLX-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20605   

TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20605(2-[3-(dimethylamino)phenyl]-1-methyl-1-{4-[2-(pipe...)
Affinity DataIC50: 71nM EC50:  19.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20605(2-[3-(dimethylamino)phenyl]-1-methyl-1-{4-[2-(pipe...)
Affinity DataIC50: 3.11E+3nM EC50:  2.18E+3nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed