BDBM206027 3-(1'-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-7- oxo-5,7-dihydro-2H,6H-spiro[furo[2,3- f]isoindole-3,4'-piperidin]-6-yl) piperidine-2,6-dione::US20260007681, Compound A33

SMILES COc1cc(N2CCC(CN3CCC4(CC3)COc3cc5c(cc34)CN(C3CCC(=O)NC3=O)C5=O)CC2)ccc1[C@@H]1c2[nH]c3ccccc3c2C[C@@H](C)N1CC(F)F

InChI Key InChIKey=JIQQCYWIYSAICS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206027   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206027BDBM206027(3-(1'-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-met...)
Affinity DataIC50: 275nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent