BDBM206021 6-(2-(9-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol- 1-yl)-3-methoxyphenyl)-3,9- diazaspiro[5.5]undecan-3-yl)-2- oxoethyl)-2-(2,6-dioxopiperidin-3- yl)-6,7-dihydropyrrolo[3,4- f]isoindole-1,3(2H,5H)-dione::US20260007681, Compound A27

SMILES COc1cc(N2CCC3(CCN(C(=O)CN4Cc5cc6c(cc5C4)C(=O)N(C4CCC(=O)NC4=O)C6=O)CC3)CC2)ccc1[C@@H]1c2[nH]c3ccccc3c2C[C@@H](C)N1CC(F)F

InChI Key InChIKey=CVBVXFWOFNDQRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206021   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206021BDBM206021(6-(2-(9-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methy...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent