BDBM206020 3-(1'-((7-(5-((1R,3R)-2-(2,2-difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1-yl) pyrimidin-2-yl)-7-azaspiro[3.5]nonan- 2-yl)methyl)-7-oxo-5,7-dihydro-2H,6H- spiro[furo[2,3-f]isoindole-3,4'-piperidin]- 6-yl)piperidine-2,6-dione::US20260007681, Compound A26

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3CCC4(CC3)CC(CN3CCC5(CC3)COc3cc6c(cc35)CN(C3CCC(=O)NC3=O)C6=O)C4)nc2)N1CCF

InChI Key InChIKey=VGDIUYRUDQZFIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206020   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206020BDBM206020(3-(1'-((7-(5-((1R,3R)-2-(2,2-difluoroethyl)-3-meth...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent