BDBM20584 1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol::tetrahydroisoquinoline derivative, 27

SMILES Oc1ccc2C(N(CCc2c1)c1ccccc1)c1ccc(F)cc1

InChI Key InChIKey=AGADFQNWGUDFRP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 20584   

TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20584(1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 285nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20584(1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 421nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20584(1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 285nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20584(1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 421nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed