BDBM205089 US9556145, example 9::methyl 2-{[(3r,6r)-1-{[6- methoxy-2-(2h-1,2,3-triazol- 2-yl)pyridin-3-yl]carbonyl}-6- methylpiperidin-3-yl] oxy}pyridine-4-carboxylate

SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccc(OC)nc2-n2nccn2)c1

InChI Key InChIKey=RFHFKIXTZWGFGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205089   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205089(US9556145, example 9 | methyl 2-{[(3r,6r)-1-{[6- m...)
Affinity DataIC50: 406nMAssay Description:TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205089(US9556145, example 9 | methyl 2-{[(3r,6r)-1-{[6- m...)
Affinity DataIC50: 1.00E+4nMAssay Description:TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details
Go to US Patent