BDBM205086 US9556145, example 6::dimethyl 2-{[(3r,6r)-6-methyl-1- {[2-(2h-1,2,3-triazol-2-yl)phenyl]- carbonyl}-piperidin-3- yl]oxy}pyridine-3,4-dicarboxylate

SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1C(=O)OC

InChI Key InChIKey=XBTOAIJVVNALGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205086   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205086(US9556145, example 6 | dimethyl 2-{[(3r,6r)-6-meth...)
Affinity DataIC50: 30.8nMAssay Description:TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205086(US9556145, example 6 | dimethyl 2-{[(3r,6r)-6-meth...)
Affinity DataIC50: 526nMAssay Description:TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details
Go to US Patent