BDBM204967 US9249085, I(aa)::US9624159, Compound I(aa)

SMILES Cc1c(F)cc(cc1CNc1c(F)ccc(OCC(O)=O)c1F)-c1cccc(F)c1

InChI Key InChIKey=JTYLYSPSSBGHFE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 204967   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Fovea Pharmaceuticals

US Patent
LigandPNGBDBM204967(US9249085, I(aa) | US9624159, Compound I(aa))
Affinity DataEC50:  3nMAssay Description:Human CHO cells expressing the recombinant human prostanoid EP2 receptor were suspended in assay medium (HBSS buffer (Invitrogen) containing 20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Fovea Pharmaceuticals

US Patent
LigandPNGBDBM204967(US9249085, I(aa) | US9624159, Compound I(aa))
Affinity DataIC50: 300nMpH: 6.0Assay Description:The competition reaction was initiated by incubation of membrane protein homogenate (20 μg protein) for 120 min at 22° C. with 0.5 nM [3H]PGE2 l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Fovea Pharmaceuticals

US Patent
LigandPNGBDBM204967(US9249085, I(aa) | US9624159, Compound I(aa))
Affinity DataIC50: 300nMAssay Description:Cell membrane homogenate from Human embryonic kidney HEK-293(T) cells expressing recombinant human prostanoid EP4 receptor was used to perform Prosta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent