BDBM204929 1-(2-((1R,3S,5R)-3-(1- isopropyl-1H-pyrazol-3- ylcarbamoyl)-2- azabicyclo[3.1.0]hexan-2-yl)- 2-oxoethyl)-1H-indazole-3- carboxamide::US9550755, example 4

SMILES CC(C)n1ccc(NC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccccc23)n1

InChI Key InChIKey=ROYSLOIULAAJAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204929   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM204929(1-(2-((1R,3S,5R)-3-(1- isopropyl-1H-pyrazol-3- ylc...)
Affinity DataIC50: 170nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2018
Entry Details
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