BDBM204928 (1r,3s,5r)-2-(2-(3-acetyl- 1h-pyrazolo[3,4-c]pyridin-1- yl)acetyl)-n-(1-(2,2,2- trifluoroethyl)-1 h-pyrazol-3- yl)-2-azabicyclo[3.1.0] hexane-3-carboxamide::US9550755, example 3

SMILES CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2ccn(CC(F)(F)F)n2)c2cnccc12

InChI Key InChIKey=ZUBQTJWUQBRZEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204928   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM204928((1r,3s,5r)-2-(2-(3-acetyl- 1h-pyrazolo[3,4-c]pyrid...)
Affinity DataIC50: 83nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
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