BDBM204847 US9242977, 84-41

SMILES CC(C)c1ncc(cc1NC(=O)Nc1cnc(Oc2ccc(cc2)-c2cnc(s2)N2CCCC2=O)nc1)C(F)(F)F

InChI Key InChIKey=LQVKCFOUUOYIOU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204847   

TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Human)
Ono Pharmaceutical

US Patent

LigandBDBM204847(US9242977, 84-41)Copy SMILESCopy InChI

Affinity DataIC50: 90nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/6/2016
Entry Details
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