BDBM204846 US9242977, 80-2

SMILES CC(C)(C)c1cc(NC(=O)Nc2cnc(Oc3ccc(cc3)-c3cnc(s3)N3CCCC3=O)nc2)n(n1)C1CCOCC1

InChI Key InChIKey=OTBSDKGMCNEZEO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204846   

TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Human)
Ono Pharmaceutical

US Patent

LigandBDBM204846(US9242977, 80-2)Copy SMILESCopy InChI

Affinity DataIC50: 70nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/6/2016
Entry Details
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