BDBM204833 US9242977, 50

SMILES FC(F)(F)c1cnc(c(NC(=O)Nc2cnc(Oc3ccc(cc3)-c3cnc(s3)N3CCCC3=O)nc2)c1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=APHUQFJCHJWGLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204833   

LigandPNGBDBM204833(US9242977, 50)
Affinity DataIC50: 40nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details
Go to US Patent

LigandPNGBDBM204833(US9242977, 50)
Affinity DataIC50: 12nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details
Go to US Patent