BDBM204818 US9546168, ex 20

SMILES COCc1nc(NC(=O)N[C@H](C)c2ccccc2)cc2[nH]nc(-c3ccnc(C)c3)c12

InChI Key InChIKey=YJIWFULGWATDBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204818   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204818(US9546168, ex 20)
Affinity DataIC50: 1.13nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
Go to US Patent