BDBM204789 US9546168, ex 2

SMILES C[C@@H](NC(=O)Nc1cc2[nH]nc(-c3ccnc(F)c3)c2c(C)n1)c1ccccc1

InChI Key InChIKey=NDTFOZBIWIQUBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204789   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204789(US9546168, ex 2)
Affinity DataIC50: 1.24nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
Go to US Patent