BDBM204785 US9243002, 83::US9243002, 86

SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2ccn3c4cccc(C#N)c4cc3c2n1)-c1ccc(F)cc1

InChI Key InChIKey=DOYHTBMIICNEKT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204785   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204785(US9243002, 86 | US9243002, 83)
Affinity DataIC50: 1.49nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204785(US9243002, 86 | US9243002, 83)
Affinity DataIC50: 1.91nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204785(US9243002, 86 | US9243002, 83)
Affinity DataIC50: 3.44nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204785(US9243002, 86 | US9243002, 83)
Affinity DataIC50: 3.05nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent