BDBM204760 US9243002, 73::US9243002, 75

SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2CCCn3c(cc4c(cccc34)C#N)-c2n1)-c1ccc(F)cc1

InChI Key InChIKey=LHLKNWNWMUIJIG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204760   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204760(US9243002, 75 | US9243002, 73)
Affinity DataIC50: 2.01nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204760(US9243002, 75 | US9243002, 73)
Affinity DataIC50: 46.7nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204760(US9243002, 75 | US9243002, 73)
Affinity DataIC50: 2.78nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204760(US9243002, 75 | US9243002, 73)
Affinity DataIC50: 43.2nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent