BDBM204721 US9243002, 58::US9243002, 59

SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2CC(CS(C)(=O)=O)n3c(cc4c(F)cccc34)-c2n1)-c1ccc(F)cc1F

InChI Key InChIKey=IVAYBSAMMPLNKQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204721   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204721(US9243002, 59 | US9243002, 58)
Affinity DataIC50: 1.52nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204721(US9243002, 59 | US9243002, 58)
Affinity DataIC50: 5.45nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204721(US9243002, 59 | US9243002, 58)
Affinity DataIC50: 1.71nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204721(US9243002, 59 | US9243002, 58)
Affinity DataIC50: 2.90nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent