BDBM204106 US9539260, H7::US9539260, H8::US9763952, Example H8

SMILES COc1cc(cnc1OC)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCCO3)cc12

InChI Key InChIKey=HQSFYUYOXHQOJM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 204106   

LigandPNGBDBM204106(US9539260, H8 | US9539260, H7 | US9763952, Example...)
Affinity DataIC50: 703nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204106(US9539260, H8 | US9539260, H7 | US9763952, Example...)
Affinity DataIC50: 5nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204106(US9539260, H8 | US9539260, H7 | US9763952, Example...)
Affinity DataIC50: 521nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204106(US9539260, H8 | US9539260, H7 | US9763952, Example...)
Affinity DataIC50: 7nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204106(US9539260, H8 | US9539260, H7 | US9763952, Example...)
Affinity DataIC50: 703nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204106(US9539260, H8 | US9539260, H7 | US9763952, Example...)
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204106(US9539260, H8 | US9539260, H7 | US9763952, Example...)
Affinity DataIC50: 521nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204106(US9539260, H8 | US9539260, H7 | US9763952, Example...)
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent