BDBM204095 US9539260, F12::US9763952, Example F12

SMILES COc1ncc(cc1C)N1CCOc2cnc(OC3CCN(C3)C(=O)C3CCS(=O)(=O)CC3)cc12

InChI Key InChIKey=VWKFJBJRKQGICM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204095   

LigandPNGBDBM204095(US9539260, F12 | US9763952, Example F12)
Affinity DataIC50: 440nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204095(US9539260, F12 | US9763952, Example F12)
Affinity DataIC50: 3nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204095(US9539260, F12 | US9763952, Example F12)
Affinity DataIC50: 440nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204095(US9539260, F12 | US9763952, Example F12)
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent