BDBM204092 US9539260, F9::US9763952, Example F9

SMILES COCC(=O)N1CC[C@@H](C1)Oc1cc2N(CCOc2cn1)c1cnc(OC)c(c1)C(F)F

InChI Key InChIKey=YDYBODJLEHCHJR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204092   

LigandPNGBDBM204092(US9539260, F9 | US9763952, Example F9)
Affinity DataIC50: 28nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204092(US9539260, F9 | US9763952, Example F9)
Affinity DataIC50: 3nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204092(US9539260, F9 | US9763952, Example F9)
Affinity DataIC50: 28nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204092(US9539260, F9 | US9763952, Example F9)
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent