BDBM204008 US9539260, D12::US9763952, Example D12

SMILES COCC(=O)N1CC[C@@H](C1)Oc1ccc2OCCN(c3cnc(OC)c(c3)C#N)c2c1

InChI Key InChIKey=JFZSBOSJMRBGRR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204008   

LigandPNGBDBM204008(US9539260, D12 | US9763952, Example D12)
Affinity DataIC50: 142nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204008(US9539260, D12 | US9763952, Example D12)
Affinity DataIC50: 3nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204008(US9539260, D12 | US9763952, Example D12)
Affinity DataIC50: 142nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204008(US9539260, D12 | US9763952, Example D12)
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent