BDBM20371 1-({4-[(1S,5R)-8-azaspiro[bicyclo[3.2.1]octane-3,2'-[1,3]dioxolane]]-2,5-difluorophenyl}methyl)-3-1H-indazol-4-ylurea::Indazole Analogue, 65

SMILES Fc1cc(N2[C@H]3CC[C@@H]2CC2(C3)OCCO2)c(F)cc1CNC(=O)Nc1cccc2[nH]ncc12

InChI Key InChIKey=BFWAWXBJKZRNRK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20371   

LigandPNGBDBM20371(1-({4-[(1S,5R)-8-azaspiro[bicyclo[3.2.1]octane-3,2...)
Affinity DataEC50:  82nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2008
Entry Details Article
PubMed