BDBM20355 1-(3-aminoisoquinolin-5-yl)-3-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-3-(trifluoromethyl)phenyl}methyl)urea::Isoquinoline Analogue, 49

SMILES Nc1cc2c(NC(=O)NCc3ccc(N4[C@H]5CC[C@@H]4CCC5)c(c3)C(F)(F)F)cccc2cn1

InChI Key

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20355   

LigandPNGBDBM20355(1-(3-aminoisoquinolin-5-yl)-3-({4-[(1R,5S)-8-azabi...)
Affinity DataEC50:  14nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2008
Entry Details Article
PubMed