BDBM203519 US9221809, 56

SMILES Cc1nccc2sc(nc12)-c1c(N[C@@H]2C[C@H](CO)[C@@H](O)[C@H]2O)nc([nH]c1=O)N1CCOCC1

InChI Key InChIKey=GEPWDSHMTDYQRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 203519   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203519(US9221809, 56)
Affinity DataIC50: 8.40nMpH: 7.2 T: 2°CAssay Description:A 20 ul reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (RP7030, Molecular...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details
Go to US Patent