BDBM20349 3-{[4-(azepan-1-yl)-2-(trifluoromethyl)phenyl]methyl}-1-isoquinolin-5-ylurea::Isoquinoline Analogue, 43

SMILES FC(F)(F)c1cc(ccc1CNC(=O)Nc1cccc2cnccc12)N1CCCCCC1

InChI Key InChIKey=ZKQRPIWAYULZNE-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20349   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

LigandBDBM20349(3-{[4-(azepan-1-yl)-2-(trifluoromethyl)phenyl]meth...)Copy SMILESCopy InChI

Affinity DataEC50:  5.70nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2008
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