BDBM20347 1-(3-chloroisoquinolin-5-yl)-3-{[4-(morpholin-4-yl)phenyl]methyl}urea::Isoquinoline Analogue, 41

SMILES Clc1cc2c(NC(=O)NCc3ccc(cc3)N3CCOCC3)cccc2cn1

InChI Key InChIKey=CJELXBBEUQTCAT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20347   

LigandPNGBDBM20347(1-(3-chloroisoquinolin-5-yl)-3-{[4-(morpholin-4-yl...)
Affinity DataEC50:  156nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2008
Entry Details Article
PubMed