BDBM20344 3-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]phenyl}methyl)-1-isoquinolin-5-ylurea::Isoquinoline Analogue, 38

SMILES O=C(NCc1ccc(cc1)N1[C@H]2CC[C@@H]1CCC2)Nc1cccc2cnccc12

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20344   

LigandPNGBDBM20344(3-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]pheny...)
Affinity DataEC50:  3.30nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2008
Entry Details Article
PubMed