BDBM20335 3-{[4-(dimethylamino)phenyl]methyl}-1-isoquinolin-5-ylurea::Isoquinoline Analogue, 29

SMILES CN(C)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1

InChI Key InChIKey=KYQAVHDPFDMOKS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20335   

LigandPNGBDBM20335(3-{[4-(dimethylamino)phenyl]methyl}-1-isoquinolin-...)
Affinity DataEC50:  157nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2008
Entry Details Article
PubMed