BDBM203294 US10227340, Example 81::US9242975, 81

SMILES CC(C)Nc1cc(Nc2ccc3ncsc3c2)ncc1-c1nc(cs1)C(=O)NC[C@H](O)c1ccccc1

InChI Key InChIKey=QAFKZOIOMLAJQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 203294   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM203294(US9242975, 81 | US10227340, Example 81)
Affinity DataIC50: 26nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substrates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM203294(US9242975, 81 | US10227340, Example 81)
Affinity DataIC50: 26nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent