BDBM202455 US9238644, 57-2A

SMILES C[C@H](C(N)=O)c1ccccc1CCc1nc(Nc2cnn(c2)C2CCN(C)CC2)ncc1C(F)(F)F

InChI Key InChIKey=RJUAJPXDDBGVQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202455   

TargetVascular endothelial growth factor receptor 2(Human)
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202455(US9238644, 57-2A)
Affinity DataIC50: 382nMpH: 7.2 T: 2°CAssay Description:Adult human umbilical vein endothelial cells (HUVEC) (Cat# CC-2519, Lonza) were seeded into clear-bottom, TC treated 12 well plates (Cat #665180, Gre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
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TargetVascular endothelial growth factor receptor 3(Human)
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202455(US9238644, 57-2A)
Affinity DataIC50: 19nMpH: 7.2 T: 2°CAssay Description:Adult human dermal lymphatic microvascular endothelial cells (HMVEC-dLyAD) (Cat# CC-2810, Lonza) were seeded into clear-bottom, TC treated 12 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent