BDBM20163 3-[(4-chlorophenyl)amino]-1-ethyl-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 11

SMILES CCN1C(=O)C(Nc2ccc(Cl)cc2)=C(C1=O)c1ccccc1

InChI Key InChIKey=SFMSQWAOWRDRJX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20163   

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20163(3-[(4-chlorophenyl)amino]-1-ethyl-4-phenyl-2,5-dih...)
Affinity DataEC50:  725nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20163(3-[(4-chlorophenyl)amino]-1-ethyl-4-phenyl-2,5-dih...)
Affinity DataEC50:  575nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed