BDBM20111 dipeptide-derived nitrile, 32::tert-butyl N-[(1S)-2-(1-benzothiophen-3-yl)-1-[(cyanomethyl)carbamoyl]ethyl]carbamate

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1csc2ccccc12)C(=O)NCC#N

InChI Key InChIKey=NUTWPMXNWZRDOX-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 20111   

TargetProcathepsin L(Human)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM20111(tert-butyl N-[(1S)-2-(1-benzothiophen-3-yl)-1-[(cy...)
Affinity DataKi:  290nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by spectrophotometric detection of the product p-nitroaniline (pNA) at waveleng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM20111(tert-butyl N-[(1S)-2-(1-benzothiophen-3-yl)-1-[(cy...)
Affinity DataKi:  300nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by spectrophotometric detection of the product p-nitroaniline (pNA) at waveleng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetProcathepsin L(Bovine)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM20111(tert-butyl N-[(1S)-2-(1-benzothiophen-3-yl)-1-[(cy...)
Affinity DataKi:  320nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by spectrophotometric detection of the product p-nitroaniline (pNA) at waveleng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetPapain(Papaya)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM20111(tert-butyl N-[(1S)-2-(1-benzothiophen-3-yl)-1-[(cy...)
Affinity DataKi:  7.40E+3nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by spectrophotometric detection of the product p-nitroaniline (pNA) at waveleng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetCathepsin K(Human)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM20111(tert-butyl N-[(1S)-2-(1-benzothiophen-3-yl)-1-[(cy...)
Affinity DataKi:  3.40E+4nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by spectrophotometric detection of the product p-nitroaniline (pNA) at waveleng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed